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Short-time low-temperature pasteurisation of human milk.

M E Wills, V E Han, D A Harris

    Early Human Development
    |October 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

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    Lower temperature and shorter pasteurization times effectively eliminate harmful bacteria in human milk. This method also preserves crucial antimicrobial protein activity, offering a gentler alternative to traditional pasteurization.

    Area of Science:

    • Food Science
    • Microbiology
    • Biochemistry

    Background:

    • Classical holder pasteurization involves high temperatures and long durations.
    • Concerns exist regarding the impact of traditional pasteurization on human milk's nutritional and immunological components.
    • Developing optimized pasteurization methods is crucial for infant nutrition and safety.

    Purpose of the Study:

    • To evaluate the efficacy of a modified pasteurization process using lower temperatures and shorter times for human milk.
    • To assess the impact of this modified pasteurization on the viability of common bacterial pathogens.
    • To determine the retention of key antimicrobial protein activity after heat treatment.

    Main Methods:

    • Human milk samples were pasteurized using the Oxford Human Milk Pasteuriser at specific temperatures and durations (e.g., 62.5°C for 5 min, 56.0°C for 15 min).

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  • Bacterial challenge studies were performed using inoculated samples of *Escherichia coli*, *Staphylococcus aureus*, and group B beta-haemolytic streptococci.
  • Antimicrobial protein activity (IgA, lactoferrin, lysozyme) was quantified before and after heat treatment.

    • Main Results:

    • Heating human milk at 62.5°C for 5 minutes completely eradicated inoculated *E. coli*, *S. aureus*, and group B streptococci.
    • A 56.0°C heat treatment for 15 minutes destroyed over 99% of these bacteria.
    • Modified pasteurization significantly preserved antimicrobial protein activity: IgA (90%), lactoferrin (91%), and lysozyme (106%) at 56°C for 15 min.

    Conclusions:

    • Human milk can be effectively pasteurized using lower temperatures and shorter time periods compared to classical holder pasteurization.
    • This optimized pasteurization method enhances the retention of vital antimicrobial proteins in human milk.
    • The findings support the use of gentler pasteurization techniques to maintain the immunological benefits of human milk.