Related Experiment Video
Updated: Aug 18, 2026
08:10
A Functional Whole Blood Assay to Measure Viability of Mycobacteria, using Reporter-Gene Tagged BCG or M.Tb (BCG lux/M.Tb lux)
Published on: September 14, 2011
[Comparative study of various routes of vaccination and testing. An instance of a killed bacterial vaccine]
Le Poumon Et Le Coeur
|January 1, 1982
Abstract:
The efficiency of intranasal subcutaneous, aerosol and digestive vaccinations with killed Klebsiella pneumoniae as vaccine was studied on the survival curves after experimental disease with pathogen K. pneumoniae I inoculated by the same routes. Results show that the local immunization is an important factor of protection and the intranasal route is very convenient.
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01:51Vaccinations
Overview
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Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...
01:21Vaccines
Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the type of...