Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Schizophrenia01:17

Schizophrenia

Schizophrenia, a term introduced by Swiss psychiatrist Eugen Bleuler in 1911, describes a severe psychological disorder marked by profound disruptions in attention, thought processes, language, emotion, and interpersonal relationships. The core feature of schizophrenia is psychosis — a state characterized by a fundamental detachment from reality. This disconnection manifests through distorted logic, impaired perception, and atypical behavior, severely affecting the lives of those diagnosed.
Biological Causes of Schizophrenia01:29

Biological Causes of Schizophrenia

Schizophrenia, a severe psychiatric disorder, arises from a complex interplay of biological factors, including genetic predisposition, structural brain abnormalities, neurotransmitter dysregulation, and developmental irregularities. These factors collectively contribute to the onset and progression of the disorder, which typically manifests in late adolescence or early adulthood.
Genetic Factors in Schizophrenia
The genetic basis of schizophrenia is strongly supported by family and twin studies.
Psychological and Sociocultural Causes of Schizophrenia01:29

Psychological and Sociocultural Causes of Schizophrenia

Schizophrenia, a complex psychiatric disorder, has been historically misunderstood. Early psychological theories attributed its origins to childhood trauma and unresponsive parenting. However, contemporary research largely rejects these notions, favoring the vulnerability-stress hypothesis. This model proposes that individuals with a genetic predisposition to schizophrenia may develop the disorder following exposure to significant environmental stressors. Notably, studies on high-risk...
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[The adolescent in general psychiatry].

Acta psychiatrica Belgica·1992
Same author

[The adolescent and the asylum].

Acta psychiatrica Belgica·1991
Same author

[Current studies on schizophrenia in adolescents].

Bulletin et memoires de l'Academie royale de medecine de Belgique·1986
Same author

[Adolescent health. Suicide and depression].

Archives belges = Belgisch archief·1984
Same author

[Drugs and drug addiction. Psychotherapeutic treatment].

Journal de pharmacie de Belgique·1982
Same author

[Image of body and family body (author's transl)].

Acta psychiatrica Belgica·1979

Related Experiment Video

Updated: May 11, 2026

Development of a Virtual Reality Assessment of Everyday Living Skills
10:32

Development of a Virtual Reality Assessment of Everyday Living Skills

Published on: April 24, 2014

[Whence dementia praecox and schizophrenia?].

P van Meerbeeck

    Acta Psychiatrica Belgica
    |May 1, 1982
    PubMed
    Summary

    Schizophrenia, once a late-onset condition, was incorrectly generalized as a juvenile psychosis by Kraepelin. This misdiagnosis caused significant harm to adolescents and their families.

    Area of Science:

    • Psychiatry
    • Psychopathology
    • Medical History

    Context:

    • The concepts of dementia praecox and schizophrenia, foundational to modern psychiatry, originated in the late 19th and early 20th centuries.
    • Historically, these conditions were not recognized as existing in the 19th century.

    Purpose:

    • To critically evaluate the historical basis of schizophrenia as a diagnostic concept.
    • To examine the evolution of psychiatric diagnostic criteria through a review of 19th and 20th-century literature.
    • To challenge the generalization of schizophrenia as a juvenile psychosis.

    Summary:

    • This review analyzes psychiatric literature from the 19th and 20th centuries.
    • It argues that the concept of schizophrenia lacks a solid historical foundation.

    More Related Videos

    Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
    08:29

    Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

    Published on: December 18, 2016

    Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
    05:14

    Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

    Published on: September 8, 2021

    Related Experiment Videos

    Last Updated: May 11, 2026

    Development of a Virtual Reality Assessment of Everyday Living Skills
    10:32

    Development of a Virtual Reality Assessment of Everyday Living Skills

    Published on: April 24, 2014

    Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
    08:29

    Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

    Published on: December 18, 2016

    Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra
    05:14

    Standardized Data Acquisition for Neuromelanin-Sensitive Magnetic Resonance Imaging of the Substantia Nigra

    Published on: September 8, 2021

  • The author posits that Kraepelin's broad application led to its misclassification as a juvenile psychosis, progressing to dementia.
  • Impact:

    • The overgeneralization of schizophrenia has led to detrimental diagnostic practices.
    • Misdiagnosis has caused significant distress for adolescents with psychosis and their families.
    • Re-evaluating historical diagnostic frameworks is crucial for accurate psychiatric care.