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Colchicine in generalized pustular psoriasis: clinical response and antibody-dependent cytotoxicity by monocytes and
Archives of Dermatological Research
|January 1, 1982
Abstract:
Four patients with generalized pustular psoriasis were treated with oral colchicine in an open study. Three of the four patients went into total remission within two weeks while receiving colchicine. The monocyte- and neutrophil function was assessed by studying antibody-dependent cytotoxicity. Increased values observed before treatment decreased during treatment. The patient who responded poorest clinically also showed less changes in monocyte- and neutrophil antibody-dependent cytotoxicity.