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The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

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Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites.

The Journal of biological chemistry·1995

Recurrent and novel LDL receptor gene mutations causing heterozygous familial hypercholesterolemia in La Habana.

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[Pulmonary surfactant. Biosynthesis. Anomalies. Therapeutic orientation]

Related Concept Videos

The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

Rapamycin, wortmannin, and the methylxanthine SQ20006 inactivate p70s6k by inducing dephosphorylation of the same subset of sites.

Recurrent and novel LDL receptor gene mutations causing heterozygous familial hypercholesterolemia in La Habana.

Structure and promoter characterization of the human stromelysin-3 gene.

Frequent loss of heterozygosity on chromosome 9, and low incidence of mutations of cyclin-dependent kinase inhibitors p15 (MTS2) and p16 (MTS1) genes in gliomas.

Molecular analysis of genetic changes in ependymomas.

Tumor size limits macrophage activation and imaging response to CD47 blockade in osteosarcoma.

Hypoxia fuels JAK/STAT-LIV1 signaling: A promising therapeutic avenue in triple-negative breast cancer.

cAmbly, a peptide derived from the star tick Amblyomma sculptum salivary gland transcriptome, attenuates inflammatory pain by activating endogenous opioid pathways.

Diosmetin attenuates chronic unpredictable mild stress induced-depression-like behavior in mice via modulation of oxidative stress, neuroinflammation, and the gut-brain axis.

Development of a first-in-class homolog-selective, covalent NOX4 inhibitor.

Phenotype-driven screening of semi-synthetic terpene analogs identifies TRX-41 as a lead compound active in chemotherapy-resistant breast cancer organoids.

Cognitive enhancement through transcranial infrared laser stimulation: Insights from our research.

Biomarkers of Subjective Tinnitus Presence and Clinical Burden: A Systematic Review.

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[Pulmonary surfactant. Biosynthesis. Anomalies. Therapeutic orientation]

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