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A rapid alpha-fetoprotein radioimmunoassay
Abstract:
A simple, reliable and inexpensive alpha-fetoprotein radioimmunoassay is described, in which polyethylene-glycol (PEG) is used as a precipitating agent of antibody-bound AFP. The concentrations of AFP found in amniotic fluid, newborn and maternal sera are in agreement with those reported by others. This assay fulfills the requirements of a screening test for fetal abnormalities and other clinical applications.