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Updated: Aug 14, 2026

A Detailed Protocol for Characterizing the Murine C1498 Cell Line and its Associated Leukemia Mouse Model
Published on: October 14, 2016
[The characterization of leukemic cells]
Some aspects of characterizing leukaemic cells are presented. The use of the FAB classification as well as the value of electronmicroscopy in cases of leukaemias unclassifiable with the lightmicroscope are discussed. Developmental stages can be assessed by means of immunological methods. Relatively new is the use of monoclonal antisera. The significance of immunological typing for clinical use is in discussion. Enzyme assays as TdT do have a contribution in diagnostics. The selective use of methods for characterizing the leukaemic cells will make it possible in future to individualize the diagnosis.
Some aspects of characterizing leukaemic cells are presented. The use of the FAB classification as well as the value of electronmicroscopy in cases of leukaemias unclassifiable with the lightmicroscope are discussed. Developmental stages can be assessed by means of immunological methods. Relatively new is the use of monoclonal antisera. The significance of immunological typing for clinical use is in discussion. Enzyme assays as TdT do have a contribution in diagnostics. The selective use of methods for characterizing the leukaemic cells will make it possible in future to individualize the diagnosis.
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