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Humoral immune function and experimental Escherichia coli infection in splenectomized dogs
Acta Microbiologica Academiae Scientiarum Hungaricae
|January 1, 1982
Abstract:
Intravenous administration of sheep red blood cells resulted in a deficient initial antibody response and provoked a much lower concentration of plaque forming cells in the blood of splenectomized dogs than in the control group. The in vitro serum opsonizing activity on Escherichia coli M-S-15 remained normal after splenectomy, and no difference was found between the test and the control group in the intravascular clearance rate of bacteria injected intravenously.