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Cerebral angiography with iohexol. A multicentre clinical trial
Acta Radiologica: Diagnosis
|January 1, 1982
Summary
This clinical trial found that the new non-ionic contrast medium, iohexol, demonstrated a favorable safety profile in 38 adult patients. Subjective reactions were less pronounced compared to conventional ionic contrast media.
Area of Science:
- Radiology and Medical Imaging
- Pharmacology
- Clinical Trials
Background:
- Conventional ionic contrast media can cause significant adverse reactions.
- There is a need for safer and better-tolerated contrast agents in medical imaging.
Purpose of the Study:
- To evaluate the safety and tolerability of the new non-ionic contrast medium iohexol.
- To compare patient-reported side effects of iohexol with traditional ionic contrast media.
Main Methods:
- An open, multicenter clinical trial was conducted.
- Thirty-eight adult patients were enrolled in the study.
- Data on side effects and patient reactions were collected.
Main Results:
- No serious adverse events or complications were reported during the trial.
- Patients experienced fewer subjective reactions with iohexol compared to ionic contrast media.
- Iohexol appears to be well-tolerated in the studied patient population.
Conclusions:
- Iohexol is a safe and well-tolerated non-ionic contrast medium.
- Iohexol offers an improved subjective experience for patients undergoing contrast-enhanced procedures.
- Further research may confirm these findings in larger patient cohorts.
