Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Epidemiology of necrotizing enterocolitis: a case control study.

B J Stoll, W P Kanto, R I Glass

    The Journal of Pediatrics
    |March 1, 1980
    PubMed
    Summary

    Low birth weight increases necrotizing enterocolitis (NEC) risk and fatality in neonates. Premature infants developing NEC later appear smaller and sicker, with other factors not significantly correlated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Maternal serum fructosamine levels and stillbirth: a case-control study of the Stillbirth Collaborative Research Network.

    BJOG : an international journal of obstetrics and gynaecology·2021
    Same author

    Stillbirth and fetal anomalies: secondary analysis of a case-control study.

    BJOG : an international journal of obstetrics and gynaecology·2020
    Same author

    Neurodevelopmental outcomes among extremely premature infants with linear growth restriction.

    Journal of perinatology : official journal of the California Perinatal Association·2018
    Same author

    Barriers to enrollment in a randomized controlled trial of hydrocortisone for cardiovascular insufficiency in term and late preterm newborn infants.

    Journal of perinatology : official journal of the California Perinatal Association·2017
    Same author

    Changing outcomes, changing policies for periviable births.

    BJOG : an international journal of obstetrics and gynaecology·2017
    Same author

    Neurodevelopmental outcomes in postnatal growth-restricted preterm infants with postnatal head-sparing.

    Journal of perinatology : official journal of the California Perinatal Association·2016

    Area of Science:

    • Neonatal Medicine
    • Pediatric Surgery
    • Gastroenterology

    Background:

    • Necrotizing enterocolitis (NEC) is a severe gastrointestinal disease affecting neonates.
    • Identifying risk factors for NEC is crucial for improving infant outcomes.

    Purpose of the Study:

    • To examine potential risk factors associated with the etiology of necrotizing enterocolitis (NEC).
    • To compare neonates with NEC to matched controls to identify significant risk factors.

    Main Methods:

    • Retrospective case-control study comparing 35 neonates with NEC to 98 matched controls.
    • Data collected included maternal history, birth history, and hospital course.
    • Analysis focused on birth weight, gestational age, and other potential predisposing factors.

    Related Experiment Videos

    Main Results:

    • Low birth weight was significantly associated with increased NEC incidence and case fatality.
    • Premature infants developing NEC later in their hospital course were smaller and sicker.
    • Prolonged rupture of membranes, infectious complications, low Apgar scores, PDA, and umbilical catheters were not found to be significant risk factors.

    Conclusions:

    • Low birth weight is a primary risk factor for necrotizing enterocolitis (NEC) in neonates.
    • Gestational age influences the timing of NEC onset and disease severity.
    • Commonly cited risk factors may represent characteristics of the general premature infant population rather than specific NEC predictors.