Effect of amiloride on conductance of toad urinary bladder

The transepithelial conductance of toad bladder epithelia and the amplitude of the fluctuations of this conductance caused by the action of the underlying smooth muscle have been further investigated. In particular, amiloride was found to reduce both tissue conductance and its fluctuating component to the same extent. Analysis suggests that the steady-state conductance of the toad urinary bladder may be associated only with the paracellular pathway for ions.