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Fulminant neonatal meningococcemia.

H W Clegg, I D Todres, F M Moylan

    American Journal of Diseases of Children (1960)
    |April 1, 1980
    PubMed
    Summary
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    Meningococcal disease is rare in infants due to maternal antibodies. A severe case of group B Neisseria meningitidis septicemia in a neonate was successfully treated, highlighting the need for consideration in infant sepsis cases.

    Area of Science:

    • Pediatrics
    • Infectious Diseases
    • Neonatology

    Background:

    • Neisseria meningitidis infections are uncommon in infants under two months old, likely due to maternal antibody transfer.
    • Neonatal meningococcal disease typically presents with a milder clinical course in reported cases.

    Observation:

    • A 25-day-old infant experienced severe meningococcemia caused by group B Neisseria meningitidis.
    • The infant survived this acute and severe presentation of the infection.

    Findings:

    • Group B Neisseria meningitidis can cause severe septicemia in neonates.
    • Despite the severity, survival is possible with appropriate medical consideration.

    Implications:

    • Clinicians should consider Neisseria meningitidis in neonates presenting with signs of septicemia.

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  • The presence of cutaneous petechiae and purpura in a neonate with sepsis warrants investigation for meningococcal infection.