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[Use of an osmotic minipump for the study of thyroxine deiodination in the rat]
Comptes Rendus Des Seances De L'Academie Des Sciences. Serie D, Sciences Naturelles
|January 21, 1980
Abstract:
Thyroidectomized Rats were implanted with an osmotic minipump delivering a continuous but small amount of T4 (2 microgram/100 g/day), mimicking therefore thyroid secretion. This experimental procedure allows a normal serum T3 level to be maintained by peripheral deiodination of T4.