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[A cell line particularly susceptible to bovine enteric Coronavirus replication: HRT 18 cells]
Comptes Rendus Des Seances De L'Academie Des Sciences. Serie D, Sciences Naturelles
|March 3, 1980
Abstract:
Bovine enteric Corona virus (BEC) multiplies spontaneously with very high efficiency in HRT 18 cells; this line established from human rectum adenocarcinoma presents some properties of the differentiated brush border cell of the intestinal villi. Titers obtained are very high (5 x 10(7) TCID 50/ml virus strain F15). The virus produced had the characteristic of BEC: shape, spikes, density 1.19, hemadsorption and hemagglutination of rat erythrocytes. Human and dog enteritic corona viruses replicate also in HRT 18 cells.