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Updated: Aug 14, 2026
14:45
Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency
Published on: August 6, 2014
Studies of mutagenicity on quiescent and proliferating hamster cell populations
Cell Biology International Reports
|March 1, 1980
Abstract:
A few known mutagens were tested on proliferating hamster cells and on cells made quiescent by L-histidinol block. No differences were found in the effectiveness of two alkylating agents and a base analogue; whereas the carcinogen 4-nitroquinoline-1-oxide was more effective on quiescent than on proliferating cells. The implications of these data on the mechanism of action of mutagens are discussed.
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