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[Dexamethasone regulation of the prolactin release induced by vasoactive intestinal peptide (VIP)]
Comptes Rendus Des Seances De L'Academie Des Sciences. Serie D, Sciences Naturelles
|March 24, 1980
Abstract:
The regulation of prolactin (PRL) secretion induced by the vasoactive intestinal peptide (VIP) has been studied on purified male Rat Pituitary PRL cells obtained by means of velocity sedimentation at unit gravity. Dexamethasone (10(-9) M) in the incubation medium inhibits the stimulatory effect of VIP (10(-7) M) on PRL release. This result suggests that glucocorticoids play an important role in the regulation of VIP effects at the effects at the pituitary level.