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Related Experiment Videos

Calcitonin in tissues of thyroidectomized monkey.

K L Becker, G Geelhoed, W O'Neill

    Experientia
    |May 15, 1980
    PubMed
    Summary

    Immunoreactive calcitonin (iCT) is found in various monkey tissues after thyroidectomy. These extrathyroidal sources of iCT may influence calcium regulation.

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    Does electronic stewardship work?

    Journal of the American Medical Informatics Association : JAMIA·2017

    Area of Science:

    • Endocrinology
    • Calcium Metabolism
    • Hormone Research

    Background:

    • Calcitonin is primarily known as a thyroid hormone.
    • Thyroidectomy (thx) removes the primary source of calcitonin.

    Purpose of the Study:

    • To investigate the presence and potential role of extrathyroidal immunoreactive calcitonin (iCT) after thyroidectomy.
    • To explore the implications of extrathyroidal iCT in calcium homeostasis.

    Main Methods:

    • Immunochemical assays were employed to detect immunoreactive calcitonin (iCT).
    • Samples were analyzed from monkeys following thyroidectomy (thx).

    Main Results:

    • Immunoreactive calcitonin (iCT) was detected in multiple monkey tissues post-thyroidectomy.
    • Significant levels of iCT were observed in tissues such as the liver, thymus, and lung.

    Conclusions:

    • Extrathyroidal tissues harbor immunoreactive calcitonin (iCT) following thyroidectomy.
    • The presence of extrathyroidal iCT suggests a potential role in regulating calcium metabolism.

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