Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Quintuplet pregnancies.

J G Schenker, N Laufer, D Weinstein

    European Journal of Obstetrics, Gynecology, and Reproductive Biology
    |May 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    THE RELATIONSHIP OF LIKING AND CHOICE TO ATTRIBUTES OF AN ALTERNATIVE AND THEIR SALIENCY.

    Multivariate behavioral research·2016
    Same author

    Cervical spinal calcinosis in a patient with systemic sclerosis.

    Diagnostic and interventional imaging·2013
    Same author

    Long-acting insulin analogues elicit atypical signalling events mediated by the insulin receptor and insulin-like growth factor-I receptor.

    Diabetologia·2010
    Same author

    Quantitative comparison of functional MRI and direct electrocortical stimulation for functional mapping.

    The international journal of medical robotics + computer assisted surgery : MRCAS·2007
    Same author

    Infertility, ovulation induction treatments and the incidence of breast cancer--a historical prospective cohort of Israeli women.

    Breast cancer research and treatment·2006
    Same author

    Influence of tissue conductivity anisotropy on EEG/MEG field and return current computation in a realistic head model: a simulation and visualization study using high-resolution finite element modeling.

    NeuroImage·2005
    Same journal

    Perinatal insights into human T-lymphotropic virus 1 in western French Guiana: Unmasking a silent disease.

    European journal of obstetrics, gynecology, and reproductive biology·2026
    Same journal

    Sentinel lymph node biopsy in atypical endometrial hyperplasia: impact on staging and adjuvant treatment.

    European journal of obstetrics, gynecology, and reproductive biology·2026
    Same journal

    Selective intraoperative multi-vessel embolization for placenta accreta spectrum: a doubly robust propensity-weighted analysis of a histologically confirmed cohort.

    European journal of obstetrics, gynecology, and reproductive biology·2026
    Same journal

    Retraction notice to "Amino acid chelated iron versus an iron salt in the treatment of iron deficiency anemia with pregnancy: A randomized controlled study" [Eur. J. Obstet. Gynecol. Reprod. Biol. 210 (2017) 242-246].

    European journal of obstetrics, gynecology, and reproductive biology·2026
    Same journal

    Fertility and pregnancy knowledge and expectations among women with a history of metabolic bariatric surgery.

    European journal of obstetrics, gynecology, and reproductive biology·2026
    Same journal

    A prospective non-randomized controlled study of a flexible panoramic electronic hysteroscope in outpatient hysteroscopic diagnosis and treatment.

    European journal of obstetrics, gynecology, and reproductive biology·2026
    See all related articles

    This study reports on five quintuplet pregnancies induced with clomiphene and HMG-HCG. Despite complications like ovarian overstimulation and preterm birth, most newborns survived and developed well.

    Area of Science:

    • Reproductive Endocrinology
    • Maternal-Fetal Medicine
    • Neonatology

    Background:

    • Induction of ovulation with clomiphene and human menopausal gonadotropin with human chorionic gonadotropin (HMG-HCG) can result in multiple gestations.
    • Quintuplet pregnancies present significant risks for both the mother and neonates.

    Purpose of the Study:

    • To report the outcomes of five quintuplet pregnancies.
    • To discuss the management of patients with multiple gestation and pregnancy outcomes.

    Main Methods:

    • Retrospective case review of five quintuplet pregnancies.
    • Analysis of maternal complications, including ovarian overstimulation and surgical interventions.
    • Assessment of neonatal outcomes, including birth weight, respiratory distress syndrome, congenital malformations, and survival rates.

    Related Experiment Videos

    Main Results:

    • Three of five women experienced ovarian overstimulation; two required surgery for ovarian cyst torsion.
    • Two pregnancies resulted in mid-trimester abortions; three delivered via cesarean section between 33-35 weeks gestation.
    • Fifteen infants were born (700-2200 g), with 8 experiencing respiratory distress syndrome and 5 having correctable malformations. Thirteen newborns survived and showed normal development. Four women conceived again.

    Conclusions:

    • Induction of ovulation with clomiphene and HMG-HCG can lead to high-order multiples with significant maternal and neonatal risks.
    • Careful patient management is crucial for optimizing outcomes in quintuplet pregnancies.
    • Despite complications, successful neonatal survival and development are achievable with appropriate medical and surgical interventions.