Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chorioretinal biopsy in dogs.

I J Constable, D H Slatter, R Horne

    Investigative Ophthalmology & Visual Science
    |June 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    A new, simplified technique for canine retinal and choroidal biopsy is presented. This method minimizes risks like bleeding and vitreous loss, preserving tissue detail for research.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Discrepancy between self-reported and actual topical steroid use in CRS-patients with nasal polyps.

    Rhinology·2026
    Same author

    Preparation for Practice: Facilitating the Transition From Student to Physician Associate.

    The clinical teacher·2025
    Same author

    Supporting patients to get the best from their osteoporosis treatment: a rapid realist review of what works, for whom, and in what circumstance.

    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·2022
    Same author

    Determinants of non-adherence to anti-TB treatment in high income, low TB incidence settings: a scoping review.

    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease·2021
    Same author

    Effects and moderators of coping skills training on symptoms of depression and anxiety in patients with cancer: Aggregate data and individual patient data meta-analyses.

    Clinical psychology review·2020
    Same author

    Protocol of a two arm randomised, multi-centre, 12-month controlled trial: evaluating the impact of a Cognitive Behavioural Therapy (CBT)-based intervention Supporting UPtake and Adherence to antiretrovirals (SUPA) in adults with HIV.

    BMC public health·2019

    Area of Science:

    • Ophthalmology
    • Veterinary Medicine
    • Surgical Techniques

    Background:

    • Ocular biopsies are crucial for diagnosing and researching retinal and choroidal diseases.
    • Existing biopsy techniques may carry significant risks, limiting their widespread application.

    Purpose of the Study:

    • To develop and validate a simplified, practical technique for canine retinal and choroidal biopsy.
    • To minimize intraoperative complications such as chorioretinal bleeding and vitreous loss.

    Main Methods:

    • A 270-degree circular scleral flap (3 mm diameter) was utilized in canine subjects.
    • Intravenous mannitol, controlled hyperventilation with hyperoxygenation, and transient systemic hypotension were employed under general anesthesia.
    • Chorioretinal specimens of 1 mm diameter were obtained.

    Related Experiment Videos

    Main Results:

    • The described technique significantly reduced risks of chorioretinal bleeding and vitreous loss.
    • Reasonable ultrastructural detail was preserved in the harvested chorioretinal specimens.
    • Repeat biopsies in the same eye were feasible without substantial complications.

    Conclusions:

    • This simplified biopsy technique offers a safe and effective method for obtaining retinal and choroidal tissue in dogs.
    • The preservation of ultrastructural detail supports its utility in detailed pathological and research studies.
    • The feasibility of repeat biopsies enhances its value for longitudinal studies.