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Primary extramedullary plasmacytoma of submaxillary lymph node.
Acta Pathologica Japonica
|March 1, 1980
Summary
A rare case of extramedullary plasmacytoma was identified in a submaxillary lymph node. This IgG, K type plasma cell tumor highlights the diverse origins of this rare cancer.
Area of Science:
- Oncology
- Pathology
- Immunohistochemistry
Background:
- Extramedullary plasmacytoma (EMP) is a rare plasma cell neoplasm.
- Approximately 70% of EMPs originate in the upper respiratory tract or oral cavity.
- Cervical lymph node metastasis occurs in 8-30% of EMP cases.
Observation:
- A case of EMP in the left submaxillary lymph node of a 63-year-old male is presented.
- Diagnosis was confirmed by identifying a monoclonal proliferation of IgG, K type plasma cells via immune antibody staining.
- Extensive examinations failed to detect primary lesions in the oral cavity or upper respiratory tract.
Findings:
- The submaxillary lymph node was identified as the primary site of the extramedullary plasmacytoma.
- Monoclonal IgG, K plasma cell proliferation confirmed the plasmacytoma diagnosis.
- The absence of a primary lesion in typical locations suggests a distinct origin.
Implications:
- This case expands the known primary sites for extramedullary plasmacytoma.
- Highlights the importance of thorough investigation for primary lesions even in atypical locations.
- Contributes to understanding the diverse clinical presentations of plasma cell neoplasms.