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Related Experiment Videos

Gastric emptying and secretion in monkeys during unavoidable shock.

B H Natelson, A Dubois

    Brain Research Bulletin
    |January 1, 1980
    PubMed
    Summary

    Repeated unavoidable shock initially had no effect on gastric acid or emptying in monkeys. However, by the final session, significant reductions in gastric acid output were observed.

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    Area of Science:

    • Physiology
    • Gastroenterology
    • Stress Research

    Background:

    • Stress can significantly impact physiological functions, including gastrointestinal processes.
    • Understanding the long-term effects of unavoidable stress on gastric acid secretion and emptying is crucial.

    Purpose of the Study:

    • To investigate the effects of repeated sessions of unavoidable shock on gastric acid and emptying rates in a primate model.
    • To determine if prolonged stress exposure alters gastric physiological responses.

    Main Methods:

    • Gastric fluid and acid secretory rates were measured.
    • Fractional emptying rates were concurrently determined.
    • Monkeys were subjected to repeated sessions of unavoidable shock.

    Main Results:

    • No significant changes in gastric acid or emptying rates were observed during the initial shock session.
    • By the final session of repeated unavoidable shock, a significant reduction in gastric acid output was noted.
    • Fractional emptying rates remained unchanged throughout the study.

    Conclusions:

    • Repeated exposure to unavoidable shock leads to a significant decrease in gastric acid secretion in monkeys.
    • Gastric emptying rates appear to be resilient to prolonged stress exposure.
    • These findings suggest a specific physiological adaptation or impairment in acid production under chronic stress conditions.

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