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Multidisciplinary audit of digoxin.

P W Keys, D DeSantis, M G Duffy

American Journal of Hospital Pharmacy

|August 1, 1978

Summary

This summary is machine-generated.

A hospital drug audit found a 17% incidence of digoxin toxicity. This review highlighted inadequate assessment of renal function and digoxin serum levels, emphasizing the need for improved drug monitoring.

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Area of Science:

Pharmacology
Clinical Pharmacy
Hospital Quality Assurance

Background:

Digoxin is a critical cardiac medication requiring careful management.
Hospital quality assurance programs are essential for optimizing drug use and patient safety.
Previous studies indicate potential challenges in digoxin monitoring and dosing.

Purpose of the Study:

To assess the incidence of digoxin toxicity within a hospital setting.
To evaluate the adequacy of digoxin monitoring practices, including renal function and serum levels.
To examine digoxin dosing patterns as part of a medical care evaluation.

Main Methods:

A multidisciplinary drug audit was conducted as part of a quality assurance program.
The study reviewed the medical records of 48 patients receiving digoxin.

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Key parameters assessed included renal function, digoxin serum levels, and dosing strategies.

Main Results:

A significant incidence of digoxin toxicity (17%) was identified.
Inadequate assessment of patient renal function was noted in several cases.
Suboptimal monitoring of digoxin serum levels contributed to toxicity risk.

Conclusions:

The study underscores the importance of rigorous digoxin monitoring protocols in hospitals.
Pharmacists play a crucial role in ensuring safe and effective digoxin therapy.
Improvements in assessing renal function and serum levels are needed to reduce digoxin toxicity.