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The management of haemophilia, Christmas disease and von Willebrand's syndrome are reviewed. The principal advances in diagnosis are the measurement of procoagulant activity, the ristocetin cofactor and the levels of the protein associated with procoagulant activity by immunologic methods. The mainstay of treatment is replacement of the coagulation factors by partially or highly purified blood products.
The management of haemophilia, Christmas disease and von Willebrand's syndrome are reviewed. The principal advances in diagnosis are the measurement of procoagulant activity, the ristocetin cofactor and the levels of the protein associated with procoagulant activity by immunologic methods. The mainstay of treatment is replacement of the coagulation factors by partially or highly purified blood products.