Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prophylactic neck irradiation.

D D Rabuzzi, C T Chung, R H Sagerman

    Archives of Otolaryngology (Chicago, Ill. : 1960)
    |August 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    External beam radiation therapy effectively treated subclinical cervical metastases in advanced head and neck cancers. This approach demonstrated a low rate of lymph node failure when used with wide-field radiation ports and primary lesion control.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Hepatic Hilar Lymph Node Reactivity at Kasai Portoenterostomy for Biliary Atresia: Correlations With Age, Outcome, and Histology of Proximal Biliary Remnant.

    Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·2017
    Same author

    Management of craniopharyngioma.

    Cancer journal (Sudbury, Mass.)·2002
    Same author

    Enhanced apoptosis and radiosensitization by combined 13-cis-retinoic acid and interferon-alpha2a; role of RAR-beta gene.

    International journal of radiation oncology, biology, physics·2001
    Same author

    Low-dose radiotherapy for macular degeneration.

    Frontiers of radiation therapy and oncology·2001
    Same author

    Neurogenic intermittent claudication related to spinal stenosis.

    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed·2001
    Same author

    Aggressive radiotherapy adjuvant to peripheral blood stem cell transplant for relapsed Hodgkin's disease.

    American journal of clinical oncology·2000
    Same journal

    Lidocaine in the treatment of Meniere's disease.

    Archives of otolaryngology (Chicago, Ill. : 1960)·1985
    Same journal

    Irradiation after neck dissection.

    Archives of otolaryngology (Chicago, Ill. : 1960)·1985
    Same journal

    Forehead lift.

    Archives of otolaryngology (Chicago, Ill. : 1960)·1985
    Same journal

    Laryngeal cyst of the thyroid cartilage.

    Archives of otolaryngology (Chicago, Ill. : 1960)·1985
    Same journal

    Metabolic facial paralysis in an infant.

    Archives of otolaryngology (Chicago, Ill. : 1960)·1985
    Same journal

    Effects of magnetic resonance imaging fields on stapedectomy prostheses.

    Archives of otolaryngology (Chicago, Ill. : 1960)·1985
    See all related articles

    Area of Science:

    • Oncology
    • Radiation Oncology
    • Head and Neck Surgery

    Background:

    • Management of subclinical cervical metastases in advanced head and neck squamous cell carcinomas is debated.
    • Treatment options include watchful waiting, elective neck surgery, and neck irradiation.
    • The concept of "sterilizing" the neck without clinical signs of metastasis is appealing.

    Purpose of the Study:

    • To evaluate the efficacy of external high-dose megavoltage radiation therapy for clinically negative necks in patients with advanced head and neck squamous cell carcinomas.
    • To assess the rate of lymph node failure following this treatment modality.

    Main Methods:

    • External high-dose megavoltage radiation therapy was administered to 152 patients.
    • Patients had clinically negative necks at presentation.

    Related Experiment Videos

  • Treatment was conducted between 1968 and 1977 at Upstate Medical Center.

    • Main Results:

    • Lymph node failures were observed in only 4% of patients.
    • This low failure rate was achieved when using wide-field radiation ports.
    • Successful control of the primary lesion was a prerequisite.

    Conclusions:

    • External high-dose megavoltage radiation therapy is an effective treatment for subclinical cervical metastases in advanced head and neck cancers.
    • Wide-field radiation ports and primary tumor control are crucial for minimizing lymph node failures.
    • This technique offers a viable alternative for managing clinically negative necks in these patients.