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Related Experiment Videos

Skeletal mass in postmenopausal women.

J F Aloia, S H Cohn, P Ross

    The American Journal of Physiology
    |July 1, 1978
    PubMed
    Summary

    Bone mineral content and total body calcium were measured in postmenopausal and osteoporotic women. Discriminant analysis correctly classified 81% of subjects, indicating distinct bone mass levels between groups.

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    Area of Science:

    • Bone Densitometry
    • Osteoporosis Research
    • Calcium Metabolism

    Background:

    • Osteoporosis is a significant health concern in postmenopausal women.
    • Accurate assessment of bone mineral density (BMD) is crucial for diagnosis and treatment.
    • Distinguishing between normal postmenopausal bone loss and osteoporosis is clinically important.

    Purpose of the Study:

    • To differentiate between normal postmenopausal women and those with osteoporosis using bone mineral content and total body calcium.
    • To assess the effectiveness of photon absorptiometry and neutron activation analysis in classifying these groups.

    Main Methods:

    • Photon absorptiometry of the radius and total body neutron activation analysis were employed.
    • Bone mineral content and total body calcium were corrected for age and body size.
    • Discriminant analysis was used to classify 115 women (71 normal postmenopausal, 44 osteoporotic).

    Main Results:

    • Discriminant analysis successfully assigned 81% of subjects to their correct group.
    • Bone mineral content and total body calcium measurements showed significant differences between normal and osteoporotic women.
    • No evidence supported a distinct subgroup with markedly different bone mass levels within the postmenopausal group.

    Conclusions:

    • Photon absorptiometry and total body neutron activation analysis are effective in distinguishing between normal postmenopausal women and those with osteoporosis.
    • Bone mass measurements can aid in the clinical assessment and management of osteoporosis.
    • Further research may explore other factors contributing to bone mass variations in postmenopausal women.

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