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Accuracy of bone mineral data.

S N Rustgi, J A Siegel, M Braunstein

AJR. American Journal of Roentgenology

|August 1, 1980

Summary

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The Norland-Cameron Bone Mineral Analyzer may overestimate bone mineral content by 6.5%. This study compared its measurements to the absolute ashing method to assess instrumental accuracy in bone density analysis.

Area of Science:

Biomedical Engineering
Orthopedics
Materials Science

Background:

Concerns exist regarding the accuracy of the Norland-Cameron Bone Mineral Analyzer.
Potential calibration errors in bone mineral analysis instruments necessitate validation.

Purpose of the Study:

To determine the instrumental accuracy of the Norland-Cameron Bone Mineral Analyzer.
To compare bone mineral content (BMC) measurements with an absolute standard.

Main Methods:

Bone samples were analyzed using the Norland-Cameron Bone Mineral Analyzer.
Absolute bone mineral content was determined using the ashing method for comparison.
Bone ash content, bone mineral density, and compact bone density were directly measured.

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Main Results:

The Norland-Cameron Bone Mineral Analyzer consistently overestimated bone mineral content by approximately 6.5%.
Direct measurements yielded an ash content of 62.9%, bone mineral density of 1.346 g/cm3, and compact bone density of 2.140 g/cm3.

Conclusions:

The Norland-Cameron Bone Mineral Analyzer exhibits a systematic overestimation of bone mineral content.
Calibration adjustments may be necessary for accurate clinical interpretation of Norland-Cameron analyzer data.