[Antigenic properties of the allergoid from ragweed pollen]

It was shown that allergoid, a preparation with decreased allergenicity and preserved immunogenicity, can be produced from ragweed growing in Stavropol. A comparative study of variations in the antigenic properties of the allergen under the effect of the temperature factor alone or a combination of the latter with formaldehyde allowed a conclusion that formaldehyde selectively neutralizes the antigenic determinants responsible for allergenicity. At the same time allergoid preserves its ability to induce antibody specific for the initial allergen in the rabbit.