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Related Experiment Videos

Fatal coma in diabetes.

G M Shenfield, I P Bhalla, R A Elton

    Diabete & Metabolisme
    |June 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Diabetic coma deaths are rare, with only 1.73% of deaths attributed to coma. Hypoglycemia, ketoacidosis, hyperosmolar, and lactic acidosis were the primary causes in this study of diabetic patients.

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    Area of Science:

    • Endocrinology
    • Metabolic Diseases
    • Clinical Medicine

    Background:

    • Diabetic coma represents a severe complication of diabetes mellitus.
    • Understanding the specific causes and prevalence of diabetic coma-related mortality is crucial for patient management.
    • Long-standing diabetes and specific treatments are associated with increased risks.

    Purpose of the Study:

    • To analyze the causes of death in a large diabetic population over an eight-year period.
    • To identify the incidence and primary causes of death due to diabetic coma.
    • To investigate factors contributing to fatal diabetic coma.

    Main Methods:

    • Retrospective analysis of mortality data from 3,113 diabetic patients over eight years.
    • Identification and categorization of deaths primarily attributed to diabetic coma.

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  • Detailed review of patient history, including duration of diabetes, treatment regimens, and precipitating factors.
  • Main Results:

    • Only 22 deaths (1.73%) out of 1,274 total deaths were primarily due to diabetic coma.
    • Specific coma types included hypoglycemia (7), ketoacidosis (8), hyperosmolar coma (3), and lactic acidosis (4).
    • Long-standing diabetes, insulin use, infection, and phenformin were associated with specific coma fatalities.

    Conclusions:

    • Death from diabetic coma is a relatively rare event in known, treated diabetic patients.
    • Hypoglycemia and ketoacidosis were the most common forms of fatal diabetic coma in this cohort.
    • Infection and specific medications like phenformin play significant roles in precipitating fatal coma.