Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primary antibiotic sensitivities by a replicator method.

L M Hendrick, V P Ackerman, P S Berriman

    Pathology
    |April 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Utilization of resource leveling to optimize ERCP efficiency.

    Irish journal of medical science·2010
    Same author

    Prospective, controlled assessment of the impact of formal evidence-based medicine teaching workshop on ability to appraise the medical literature.

    Irish journal of medical science·2009
    Same author

    In vitro studies of ciprofloxacin and survey of resistance patterns in current isolates.

    Diagnostic microbiology and infectious disease·1990
    Same author

    Antibiotic resistance in Australia with special reference to sulbactam/ampicillin.

    Diagnostic microbiology and infectious disease·1989
    Same author

    In vitro activity of A-56619 and A-56620 against multi-resistant and routine clinical isolates.

    Chemotherapy·1988
    Same author

    The role of chlamydial antibodies in an in vitro fertilization program.

    Fertility and sterility·1987
    Same journal

    Impact of the 2025 Endocrine Society clinical practice guideline on the diagnosis and management of primary aldosteronism for the clinical laboratory.

    Pathology·2026
    Same journal

    Cribriform intraductal carcinoma of the prostate may have a greater prognostic impact even than Gleason grade 5 conventional prostatic adenocarcinoma.

    Pathology·2026
    Same journal

    Bordetella pertussis: emerging epidemiology, diagnosis and management.

    Pathology·2026
    Same journal

    Development and validation of a real-time polymerase chain reaction for the detection of Haycocknema perplexum.

    Pathology·2026
    Same journal

    Recent advances in the understanding of TP53 in haematological malignancies.

    Pathology·2026
    Same journal

    Concurrent renal amyloid light chain amyloidosis, light chain crystalline podocytopathy and light chain proximal tubulopathy: a case report.

    Pathology·2026
    See all related articles

    A new replicator method for urine specimen antibiotic sensitivity testing provides results within 24 hours. This rapid diagnostic tool accurately identifies effective antibiotics for most infections, aiding timely treatment decisions.

    Area of Science:

    • Clinical Microbiology
    • Diagnostic Technology
    • Infectious Diseases

    Background:

    • Accurate antibiotic sensitivity testing is crucial for effective urinary tract infection (UTI) treatment.
    • Conventional methods can be time-consuming, delaying appropriate antimicrobial therapy.
    • Rapid diagnostics are needed to optimize patient outcomes and combat antimicrobial resistance.

    Purpose of the Study:

    • To describe and evaluate a novel replicator method for primary sensitivity testing of urine specimens.
    • To compare the performance of the replicator method against conventional sensitivity testing techniques.
    • To assess the accuracy and speed of the replicator method in identifying suitable antibiotics.

    Main Methods:

    • A replicator method was developed for primary sensitivity testing of urine samples.

    Related Experiment Videos

  • The replicator method was used to analyze 438 urine specimens.
  • Results from the replicator method were compared with those from standard, conventional sensitivity tests.

    • Main Results:

    • The replicator method successfully identified a suitable antibiotic for 431 out of 438 (98.4%) specimens.
    • The method yielded a potentially misleading incorrect result in 14 instances (3.2%).
    • In all 14 misleading cases, the replicator method also provided several correct sensitivity reports.

    Conclusions:

    • The replicator method offers a rapid and largely accurate approach for urine specimen antibiotic sensitivity testing.
    • Results are available within 24 hours, significantly faster than many conventional methods.
    • While generally reliable, careful interpretation is needed due to a small percentage of misleading results.