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Related Experiment Videos

[A technic for parenteral feeding in a rat model].

D Futtig, M Mory, G Schmoz

    Zeitschrift Fur Experimentelle Chirurgie
    |January 1, 1980
    PubMed
    Summary

    This study details a central vein catheterization method in rats using the external jugular vein. This technique enables effective long-term infusion therapy in animal research.

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    Immunolesion-induced loss of cholinergic projection neurones promotes β-amyloidosis and tau hyperphosphorylation in the hippocampus of triple-transgenic mice.

    Neuropathology and applied neurobiology·2013

    Area of Science:

    • Veterinary Medicine
    • Surgical Techniques
    • Animal Models

    Context:

    • Effective long-term infusion therapy is crucial for various animal experiments.
    • Standard catheterization methods may have limitations in rats.
    • Minimally invasive techniques are preferred for animal welfare.

    Purpose:

    • To describe a reliable method for central vein catheterization in rats.
    • To facilitate long-term infusion therapy in rodent research.
    • To provide a surgical approach via the external jugular vein.

    Summary:

    • A surgical technique for central vein catheterization in rats is presented.
    • The procedure involves accessing the external jugular vein.
    • This method allows for successful and sustained infusion therapy.

    Impact:

    • Enables advanced pharmacokinetic and pharmacodynamic studies in rats.
    • Improves the feasibility of chronic drug delivery in preclinical research.
    • Offers a valuable tool for researchers utilizing rat models.

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