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Related Experiment Videos

Evaluation of the ASTRA 4 new microprocessor-controlled electrolyte analyzer.

A E Hartmann, J R Fillbach

    American Journal of Clinical Pathology
    |September 1, 1980
    PubMed
    Summary

    The Beckman ASTRA 4 analyzer offers reliable multichannel electrolyte analysis for sodium, potassium, chloride, and CO2. Its programmable features and efficiency make it suitable for both routine and stat laboratory testing.

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    Area of Science:

    • Clinical Chemistry
    • Medical Diagnostics
    • Analytical Instrumentation

    Background:

    • Accurate electrolyte measurement is crucial for patient diagnosis and management.
    • Existing analyzers may have limitations in throughput, programmability, or sample volume.

    Purpose of the Study:

    • To evaluate the performance of the new Beckman ASTRA 4 multichannel chemistry analyzer.
    • To assess its suitability for routine and stat electrolyte analysis.

    Main Methods:

    • The Beckman ASTRA 4 was evaluated for sodium, potassium, chloride, and CO2 analysis.
    • Methods included ion-selective electrodes, differential rate pH measurement, and coulometric titration.
    • Reproducibility, linearity, and correlation with established methods were assessed.

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    Main Results:

    • Excellent day-to-day reproducibility was observed (CVs: Na+ 0.8%, K+ 1.2%, Cl- 0.9%, CO2 5.9%).
    • Linearity ranged from 1.0-200 mmol/l across the measured electrolytes.
    • High correlation was found between the ASTRA 4 and comparison laboratory methodologies.

    Conclusions:

    • The Beckman ASTRA 4 demonstrates acceptable performance for medical usefulness.
    • The analyzer offers high throughput (60 samples/hour) and rapid stat results (within 8.5 minutes).
    • Programmable test selection optimizes reagent consumption and minimizes sample volume (approx. 130 µl).