Related Experiment Video
Updated: Aug 13, 2026

Coordinate Mapping of Hyolaryngeal Mechanics in Swallowing
Published on: May 6, 2014
Some observations on the development of the human hyoid bone
Insights
The human hyoid bone develops an interzone between its body and greater cornua during chondrification. This study reveals this interzone can form a joint (diarthrosis) or persist as a cell line, explaining adult anatomy.
Area of Science:
- Anatomy
- Embryology
- Developmental Biology
Background:
- The human hyoid bone's development and adult structure are complex.
- Understanding the developmental stages of the hyoid bone is crucial for anatomical accuracy.
Purpose of the Study:
- To investigate the developmental process of the human hyoid bone.
- To elucidate the formation of the interzone between the hyoid body and greater cornua.
- To explain the embryological basis for the adult hyoid bone's structure.
Main Methods:
- Examination of human hyoid bone development across various stages.
- Histological analysis of chondrification and interzone formation.
- Observation of joint cavity development and cell persistence.
Main Results:
- A distinct interzone forms between the hyoid body and greater cornua during chondrification.
- This interzone reduces in thickness during development.
- Joint cavities or persistent cell lines are observed in fetuses and newborns, indicating diarthrosis formation.
Conclusions:
- The observed developmental stages represent the formation of a diarthrosis between the hyoid corpus and cornu majus.
- Embryological findings confirm the adult connection of the lesser horn to the cornu majus, not the body.
Abstract:
Investigations on the human hyoid bone in several developmental stages reveal that with the chondrification of the mesenchymal blastema a typical interzone between the body and the greater cornua is formed. This disc of closely packed blastemal cells, distinct and broad in the earlier stages, is reduced in thickness in the course of further development. In fetuses between 5 and 6 months old and in newborns the formation of joint cavities can be seen in some cases. In other cases, however, a small transverse line of cells persists between the two cartilaginous elements. These findings are interpreted as different developmental stages of a diarthrosis generally formed between the corpus and the cornu majus. The fact that in the adult the lesser horn is connected directly to the cornu majus and not to the body is confirmed by the embryological investigations reported in this study.
Related Concept Videos
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
The Hyoid Bone
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Bone Formation by Endochondral Ossification
Muscles of the Anterior Neck

