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Related Experiment Videos

Cost-effectiveness of an immunization programme in Indonisia.

H N Barnum, D Tarantola, I F Setiady

    Bulletin of the World Health Organization
    |January 1, 1980
    PubMed
    Summary

    An expanded immunization program for diphtheria, pertussis, tetanus, and tuberculosis is highly cost-effective compared to treatment. Including BCG vaccination in a joint program enhances economic justification, even if not cost-efficient alone.

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    Area of Science:

    • Public Health
    • Health Economics
    • Vaccinology

    Background:

    • Immunization programs are crucial for disease prevention.
    • Assessing the economic viability of public health interventions is essential for resource allocation.
    • The cost-effectiveness of combined vaccination strategies requires thorough evaluation.

    Purpose of the Study:

    • To evaluate the cost-effectiveness of an expanded immunization program.
    • To analyze the economic justification of individual vaccine components within a broader program.
    • To determine the economic impact of including BCG vaccination in a combined immunization schedule.

    Main Methods:

    • Economic analysis based on hypothetical program impact estimates.
    • Sensitivity analysis to test the robustness of cost-effectiveness findings.

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  • Separate evaluation of DPT-tetanus toxoid and BCG components.

    • Main Results:

    • The expanded immunization program for diphtheria, pertussis, tetanus, and tuberculosis is highly cost-effective versus treatment.
    • Sensitivity tests confirm cost-effectiveness even with increased costs and reduced benefits.
    • BCG vaccination, while not independently justifiable, becomes economically sound within a joint immunization program (vaccine efficacy of 0.5).

    Conclusions:

    • Expanded immunization programs offer significant economic benefits compared to disease treatment.
    • Integrating individual vaccines, like BCG, into larger programs can improve overall cost-effectiveness.
    • Findings support WHO's expanded immunization strategies and highlight the economic advantages of combined vaccination approaches.