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Related Experiment Videos

Fulminant colitis complicating gold therapy.

A G Fam, T W Paton, C J Shamess

    The Journal of Rheumatology
    |July 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

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    Gold therapy can cause a rare but serious complication: enterocolitis. This summary highlights two cases of severe colitis linked to gold treatment for rheumatoid arthritis, emphasizing early diagnosis and intervention.

    Area of Science:

    • Gastroenterology
    • Rheumatology
    • Pharmacology

    Background:

    • Gold therapy (chrysotherapy) is used for rheumatoid arthritis.
    • Enterocolitis is a rare complication associated with gold therapy.

    Observation:

    • Two cases of fulminant colitis occurred during gold therapy for rheumatoid arthritis.
    • One patient underwent colectomy, while the other received intensive medical treatment.

    Findings:

    • Colonic biopsies revealed extensive ulcerations, edema, hemorrhages, and mononuclear cell infiltration.
    • These findings indicate severe inflammation and tissue damage in the colon.

    Implications:

    • Early recognition and prompt treatment are crucial for managing this serious complication.

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  • This highlights the need for vigilance in patients receiving gold therapy for rheumatoid arthritis.