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Immunity to Lancefield's group E Streptococcus: passive protection of swine
American Journal of Veterinary Research
|July 1, 1978
Summary
Serum from convalescent pigs provided resistance against streptococcic lymphadenitis. This study shows potential for passive immunity in controlling Streptococcus suis infections in swine.
Area of Science:
- Veterinary Medicine
- Immunology
- Bacteriology
Background:
- Streptococcic lymphadenitis in swine, caused by Streptococcus spp.
- Importance of Streptococcus suis in swine health
- Limited understanding of passive immunity against swine streptococcic lymphadenitis
Purpose of the Study:
- To investigate the efficacy of serum from convalescent swine in conferring resistance against experimental streptococcic lymphadenitis.
- To evaluate the protective effects of passive immunization against Streptococcus suis infection in pigs.
Main Methods:
- Random allotment of healthy swine into three groups (two treatment, one control).
- Parenteral administration of convalescent swine serum to treatment groups.
- Oral exposure of all groups to Lancefield's group E Streptococcus sp.
- Observation and assessment of disease development over three weeks.
Main Results:
- Pigs receiving convalescent serum (treatment groups) showed considerable resistance to developing streptococcic lymphadenitis.
- Control pigs exhibited little resistance and developed the disease.
- Passive immunity conferred by convalescent serum significantly reduced disease incidence.
Conclusions:
- Serum from swine in the convalescent stage of streptococcic lymphadenitis can provide passive immunity.
- Passive immunization is a potential strategy for controlling Streptococcus suis infections in swine herds.
- Further research intoStreptococcus suis pathogenesis and immunity is warranted.
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