[Hemodynamics and gas exchange in experimental pulmonary microembolism]

Parameters of hemodynamics and gas exchange were studied in experiments in 25 dogs having experimental microembolism of the lungs. Microembolism was found to result in an abrupt increase of the pulmonary arterial pressure and resistance of lungs, stable hypoxemia with phenomena of metabolic acidosis, incrsed intrapulmonary shunting and the ventilation/perfusion ratio. The mechanisms of hemodynamic and respiratory rearrangement are discussed.