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A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice
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A Method to Study the Impact of Chemically-induced Ovarian Failure on Exercise Capacity and Cardiac Adaptation in Mice

Published on: April 7, 2014

Influence of exogenous estrogen on oocytic depletion induced by 7,12-dimethylbenz[alpha]anthracene in mice

K Manoharan, A R Rao

    Cancer Letters
    |October 1, 1980
    PubMed

    Abstract:

    The influence of exogenous estrogen on the action of 7,12-dimethylbenz[alpha]anthracene (DMBA) on ovaries of Swiss albino mouse has been studied. DMBA elicits the depletion of oocytes; but concomitant administration of estrogen with DMBA reduces this loss of oocytic population significantly.

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