[Mitotic activity changes in serous ovarian cystadenocarcinomas under treated with chemotherapy]

The intraoperative material was examined morphologically in 254 patients, aged from 31 to 71, with serous ovarian cystadenocarcinoma. One hundred patients were not given a preoperative course of chemotherapy, and 154 patients were administered thio-TEPA in various dosage. As a dose of the drug was increased less mitotic activity was noted, which may serve as a quantitative indicator of the chemotherapy efficacy.