Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ocular defects and short stature.

R C Polomeno, C Staudenmaier, H J Guyda

    Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie
    |July 1, 1980
    PubMed
    Summary

    Ocular anomalies in short children may indicate hypothalamic-pituitary or intracranial issues. Early diagnosis of these visual, endocrine, and neurological problems is crucial for timely intervention and treatment.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Vascular Amputees: A Study in Disappointment.

    Journal of bioethical inquiry·2022
    Same author

    Electron Cooling in a Magnetically Expanding Plasma.

    Physical review letters·2016
    Same author

    Jaw muscle tension after succinychloline in children undergoing strabismus surgery.

    Canadian journal of anaesthesia = Journal canadien d'anesthesie·2016
    Same author

    Estimating ON and OFF contributions to the photopic hill: normative data and clinical applications.

    Documenta ophthalmologica. Advances in ophthalmology·2014
    Same author

    Diuresis resulting from intravenous infusion of urine.

    Federation proceedings·2010
    Same author

    Further observations on the toxic factor in ischemic compression shock.

    Federation proceedings·2010

    Area of Science:

    • Pediatric Endocrinology
    • Neuro-ophthalmology
    • Developmental Biology

    Background:

    • Short stature in children can be associated with complex underlying medical conditions.
    • Ocular anomalies may serve as early indicators of systemic or intracranial abnormalities.
    • The interplay between ocular, endocrine, and neurological systems is critical for normal development.

    Observation:

    • This study details three cases of short stature with distinct ocular, endocrine, and neurological findings.
    • Case 1 presented with basal encephalocele, agenesis of the corpus callosum, and varied optic nerve and retinal abnormalities.
    • Case 2 exhibited septo-optic dysplasia, while Case 3 had Rieger's anomaly.

    Findings:

    • All three children demonstrated deficient or abnormal growth hormone responses.
    • Two of the three children also presented with additional pituitary hormonal abnormalities.
    • The observed spectrum of conditions suggests a developmental arrest during organogenesis.

    Implications:

    • Early identification of ocular anomalies in short children is vital for detecting potential hypothalamic-pituitary dysfunction.
    • Comprehensive endocrinologic and neurologic investigations are essential for accurate diagnosis.
    • Prompt therapeutic interventions can significantly improve outcomes for affected children.

    Related Experiment Videos