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Related Experiment Videos

Topical antimicrobial cream sensitivity testing.

G T Rodeheaver, S Gentry, L Saffer

    Surgery, Gynecology & Obstetrics
    |December 1, 1980
    PubMed
    Summary
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    The needle extrusion test offers rapid, effective bacteriologic monitoring for burn wounds. This method aids in selecting topical antimicrobials, potentially benefiting other wound types.

    Area of Science:

    • Microbiology
    • Infectious Diseases
    • Wound Care

    Background:

    • Bacteriologic monitoring of burn wounds is crucial for effective treatment.
    • Topical antimicrobial sensitivity testing guides therapeutic choices.
    • Existing methods like disk diffusion and agar-well diffusion are time-consuming.

    Purpose of the Study:

    • To evaluate the needle extrusion test for routine bacteriologic monitoring of burn wounds.
    • To compare the efficiency of the needle extrusion test with other antimicrobial sensitivity tests.
    • To assess the potential applicability of the needle extrusion test for other wound types.

    Main Methods:

    • Routine use of the needle extrusion test for all burn patients.
    • Comparison of needle extrusion test completion time with disk diffusion and agar-well diffusion tests.

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  • Monitoring microflora of burn patients every other day.

    • Main Results:

    • The needle extrusion test is a rapid method, completed within five minutes by experienced technicians.
    • Disk diffusion and agar-well diffusion tests take significantly longer (two and five times longer, respectively).
    • The time efficiency of the needle extrusion test is critical for frequent monitoring of multiple patients.

    Conclusions:

    • The needle extrusion test is an integral and efficient tool for bacteriologic monitoring of burn wounds.
    • Its speed makes it preferable to other methods for routine clinical use.
    • The needle extrusion test may have potential applications in topical antibiotic selection for other wound types, pending further clinical studies.