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Gas absorption in the middle ear.

E I Cantekin, W J Doyle, D C Phillips

    The Annals of Otology, Rhinology & Laryngology. Supplement
    |May 1, 1980
    PubMed
    Summary
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    Middle ear pressure in monkeys was studied. Anesthetized animals developed negative middle ear pressure, especially after oxygen gas politzerization, suggesting a gas absorption mechanism.

    Area of Science:

    • Physiology
    • Otolaryngology

    Background:

    • The middle ear (ME) cavity's gas composition and pressure regulation are crucial for auditory function.
    • Understanding gas absorption dynamics in the ME is essential for diagnosing and treating middle ear pathologies.

    Purpose of the Study:

    • To investigate the gas absorption process within the middle ear cavity.
    • To determine the effect of altered gas composition on middle ear pressure.
    • To propose a mechanism for negative middle ear pressure development.

    Main Methods:

    • Serial tympanometry was used to monitor middle ear pressure in alert and anesthetized rhesus monkeys.
    • Middle ear gas composition was altered via air and oxygen gas politzerization in anesthetized subjects.

    Main Results:

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    • Alert monkeys exhibited stable middle ear pressure around zero.
    • Anesthetized monkeys showed a plateau of negative middle ear pressure (-60 mm H2O).
    • Politzerization with oxygen resulted in a significantly greater negative pressure (-730 mm H2O) compared to air (-400 mm H2O).

    Conclusions:

    • The physiological middle ear gas composition is similar to the ambient environment, with a low rate of gas absorption.
    • Altering middle ear gas composition can induce significant negative pressure.
    • A novel mechanism for negative middle ear pressure development is proposed based on these findings.