[Physiological characteristics of immobilized cells of Streptococcus lactis, Moscow State University strain]

Immobilized cells of Streptococcus lactis, strain MSU, synthesized nisin by 20--30 per cent of the possible maximum antibiotic production level. The immobilized cells of the Streptococcus synthesized nisin by 40--50 per cent probably at the expense of the cell nutrient pools and by 50--60 per cent at the expense of the medium nutrient consumption. The electron microphotographs showed that the cells of Str. lactis, strain MSU, preserved their usual appearance in the granules of polyacrylamide gel 24 hours after immobilization. In 3 weeks there were observed structural changes in the cell wall and inner membranes resulting in the cell lysis after presence in the granules for 3 months.