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[Disinfection of surgical silk with decamethoxin, antibiotics and their combinations]

G K Paliĭ, A D Iukhimel, I F Onofreĭchuk

    Antibiotiki
    |July 1, 1978
    PubMed

    Insights

    A two-step disinfection process using decametoxin and antibiotics ensures surgical silk sterility. This method effectively eliminates bacteria without compromising suture strength, crucial for surgical applications.

    Area of Science:

    • Microbiology
    • Materials Science
    • Infectious Disease Control

    Context:

    • Surgical site infections remain a significant concern in healthcare.
    • Sterilization of surgical materials is paramount to prevent microbial contamination.
    • Standard disinfection protocols may not always achieve complete microbial eradication.

    Purpose:

    • To evaluate the efficacy of decametoxin and antibiotic combinations for disinfecting infected surgical threads.
    • To determine the optimal disinfection protocol for achieving absolute sterility of surgical silk.
    • To assess the impact of decametoxin treatment on the tensile strength of surgical silk.

    Summary:

    • A sequential disinfection approach involving 0.1% decametoxin for 15 minutes followed by antibiotic treatment for 105 minutes achieved absolute sterility on surgical silk infected with various bacteria (Staphylococcus aureus, Proteus vulgaris, Bacillus anthracis, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis).
    • Neither decametoxin nor antibiotic combinations alone provided complete microbial destruction.
    • Prolonged exposure of surgical silk to 0.1% decametoxin for 24 hours did not adversely affect its tensile strength.

    Impact:

    • Establishes a highly effective, two-stage disinfection protocol for surgical threads, enhancing patient safety.
    • Provides evidence for the preservation of surgical material integrity post-disinfection.
    • Offers a potential improvement over existing sterilization methods for surgical sutures in clinical settings.

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