3-Alkyl(aryl)-piperazinoalkyl derivatives of 5,5-diphenylhydantoin

The new obtained N3-alkyl- or arylpiperazinoalkyl substituted derivatives of 5,5-diphenylhydantoin weakly affect the spontaneous motility and the hypermotility induced by amphetamine. They did not show the anticonvulsive activity. Compounds containing the methyl (or phenyl)-piperazine moiety connected by the three-carbon chain with the N3 atom of the hydantoin ring show the strongest activity in the potentiation of the central effect of DOPA.