Effect of bromocryptine in oligozoospermic men with hyperprolactinaemia

13 patients with oligozoospermia, showing high prolactin serum levels but no signs of a prolactinoma, were treated with the specific prolactin inhibitor bromocryptine. After a 50 day treatment period an increase of sperm count in 6 cases, a decrease in 2 cases and no alteration in 5 cases was observed. Other semen parameters were not altered. Serum prolactin was significantly lowered. No explanation for the influence of inhibition of prolactin release on spermatogenesis can be given at present. The value of this therapy therefore is doubtful.