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[Side-effects of corticosteroid therapy (author's transl)]
Summary
Corticosteroid therapy can cause significant side effects, impacting metabolism, bone health, and more. Careful risk-benefit assessment is crucial for patient safety and effective treatment.
Area of Science:
- Endocrinology
- Pharmacology
Context:
- Corticosteroid therapy is widely used but associated with numerous adverse effects.
- Understanding these side effects is critical for safe clinical practice.
Purpose:
- To review the adverse effects and side effects of corticosteroid therapy.
- To outline guidelines for corticosteroid use and contraindications.
- To discuss the impact of pharmacodynamic therapy on metabolism and mineral balance.
Summary:
- Discusses metabolic effects (carbohydrates, proteins, fats), mineral balance disturbances (steroid diabetes, osteoporosis, myopathies), and properties of synthetic corticosteroids.
- Details complications in the gastrointestinal tract, blood clotting, infection course, psychic behavior, skin, and eyes.
- Provides recommendations for patient supervision and information, emphasizing benefit-risk assessment.
Impact:
- Informs clinicians on managing corticosteroid side effects.
- Aids in optimizing corticosteroid therapy by balancing benefits against risks.
- Enhances patient safety through informed supervision and management strategies.