Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Mannitol.

S E Warren, R C Blantz

    Archives of Internal Medicine
    |March 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Mannitol, an osmotic diuretic, offers versatile clinical applications including prophylactic use, diagnostic aid, and therapy for oliguric states. Its properties also benefit patients with refractory edema, intoxications, intracranial hypertension, and dialysis dysequilibrium.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Tubuloglomerular feedback responses of the downstream efferent resistance: unmasking a role for adenosine?

    Kidney international·2007
    Same author

    Coordination of kidney filtration and tubular reabsorption: considerations on the regulation of metabolic demand for tubular reabsorption.

    Acta physiologica Hungarica·2007
    Same author

    Making sense of the sensor: mysteries of the macula densa.

    Kidney international·2006
    Same author

    Suppression of inducible nitric oxide generation by agmatine aldehyde: beneficial effects in sepsis.

    Journal of cellular physiology·2001
    Same author

    The outcome of non-selective vs selective nitric oxide synthase inhibition in lipopolysaccharide treated rats.

    Journal of nephrology·2001
    Same author

    Polyamine transport system mediates agmatine transport in mammalian cells.

    American journal of physiology. Cell physiology·2001
    Same journal

    Elevated CK-MB With Normal Total Creatine Kinase Levels in Patients Undergoing Maintenance Hemodialysis-Reply.

    Archives of internal medicine·2017
    Same journal

    Occult Carbon Monoxide Poisoning-Reply.

    Archives of internal medicine·2017
    Same journal

    Acquired Immune Deficiency Syndrome-Reply.

    Archives of internal medicine·2017
    Same journal

    Heparin Side Effects-Reply.

    Archives of internal medicine·2017
    Same journal

    Humanizing primary care medicine begins with stress.

    Archives of internal medicine·2017
    Same journal

    Legend omitted and number misrepresented.

    Archives of internal medicine·2013
    See all related articles

    Area of Science:

    • Pharmacology
    • Nephrology
    • Critical Care Medicine

    Background:

    • Mannitol is an osmotic diuretic with established clinical uses.
    • Optimal usage guidelines are not precisely defined by controlled studies.
    • Clinical experience and published literature form a basis for consensus on its application.

    Purpose of the Study:

    • To review the diverse clinical applications of mannitol.
    • To discuss the renal and systemic effects of mannitol.
    • To establish a consensus on the optimal use of mannitol based on available evidence and experience.

    Main Methods:

    • Literature review of published works on mannitol.
    • Analysis of clinical experience with mannitol.
    • Synthesis of information to form a consensus on optimal use.

    Related Experiment Videos

    Main Results:

    • Mannitol serves as a prophylactic agent, diagnostic aid, and therapeutic option for oliguric states.
    • Its diuretic properties are beneficial for refractory edema and specific intoxications (aspirin, barbiturates, bromide).
    • As an extracellular solute, mannitol can reduce intracranial hypertension and dialysis dysequilibrium symptoms.

    Conclusions:

    • Mannitol is a versatile osmotic diuretic with broad clinical utility.
    • Evidence supports its use in various conditions despite limited controlled trials.
    • Further research may refine optimal therapeutic strategies for mannitol.