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[Quantitative study of left ventricular function by two-dimensional echocardiography].

P Guéret, E Corday

    Archives Des Maladies Du Coeur Et Des Vaisseaux
    |March 1, 1981
    PubMed
    Summary
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    Two dimensional echocardiography accurately calculates left ventricular volumes and ejection fractions. This non-invasive method allows real-time cardiac function assessment for disease monitoring and treatment evaluation.

    Area of Science:

    • Cardiology
    • Medical Imaging
    • Echocardiography

    Background:

    • Accurate measurement of left ventricular (LV) volumes and ejection fraction (EF) is crucial for assessing cardiac function.
    • Traditional methods like cineventriculography are invasive.

    Purpose of the Study:

    • To compare the accuracy of two-dimensional echocardiography (2D echo) with cineventriculography for calculating LV volumes and EF.
    • To evaluate 2D echo's utility in assessing cardiac function in patients with ischemic heart disease.

    Main Methods:

    • Experimental study in dogs and a clinical study in 12 patients with ischemic heart disease.
    • LV volumes and EF calculated using Simpson's method and a simplified 5/6 AL formula from 2D echo.
    • Comparison with cineventriculography (angiography) as the gold standard.

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    Main Results:

    • In dogs, 2D echo showed excellent correlation with angiography for end-diastolic volume (r=0.94), end-systolic volume (r=0.97), and EF (r=0.89).
    • In patients, 2D echo correlated well with angiography for end-systolic volume (r=0.91) and excellently for EF (r=0.97), though it underestimated end-diastolic volume (14%) and end-systolic volume (13%).

    Conclusions:

    • Two-dimensional echocardiography is a reliable, non-invasive method for calculating LV volumes and EF.
    • This technique enables real-time, beat-to-beat quantitative assessment of cardiac function, useful for disease progression monitoring and therapeutic response evaluation.