[Restimulation of anti-rhesus antibodies and anti-HLA immunization]

Anti-Rh antibodies were restimulated in 32 previously immunized volunteers by injection of small amounts (2 ml) of Rh + fresh blood. The anti-HLA immunization was investigated during this procedure. None of the 10 men developed anti-HLA antibodies. Contrarily 45% of the 22 women showed an anti-HLA antibody before or during the immunization procedure. The HLA type of the husband and of the injected blood was performed to try to explain the specificity of the anti-HLA antibodies.