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Related Experiment Videos

Dynamic computed tomography of the brain: techniques, data analysis, and applications.

D Norman, L Axel, W H Berninger

    AJR. American Journal of Roentgenology
    |April 1, 1981
    PubMed
    Summary

    Rapid sequence computed tomography (CT) scans can provide quantitative data on brain blood flow using corrected mean transit time. This method enhances the analysis of intracranial events by identifying specific brain structures and improving image clarity.

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    Area of Science:

    • Neuroimaging
    • Radiology
    • Medical Physics

    Background:

    • Rapid sequence computed tomography (CT) scans offer potential for studying intracranial physiology.
    • Visual inspection of CT data limits the extraction of valuable digital information.

    Observation:

    • The study explores quantitative analysis of rapid sequence CT scans.
    • Focuses on intravenous contrast material bolus injection for hemodynamic assessment.

    Findings:

    • Corrected mean transit time provides quantitative data on relative hemispheric blood flow.
    • Histogram-based areas of interest enable accurate identification of brain structures (arteries, gray/white matter).
    • Gamma variate curve fitting reduces noise, enhancing data reliability.

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    Implications:

    • Transit time analysis can be expanded to create functional CT images.
    • This approach improves the diagnostic utility of rapid sequence CT for neurological conditions.
    • Enables more precise characterization of cerebral blood flow dynamics.